Description
Human Deoxyhypusine Synthase (DHS) is vital for the first step of hypusine biosynthesis. DHS catalyzes the NADdependent oxidative cleavage of spermidine, the subsequent transfer of the butylamine moiety of spermidine to the epsilonamino group of a specific lysine residue of the eIF5A precursor protein to form the intermediate deoxyhypusine residue